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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1CC
All Species:
58.79
Human Site:
Y144
Identified Species:
80.83
UniProt:
P36873
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36873
NP_002701.1
323
36984
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Chimpanzee
Pan troglodytes
XP_001144148
355
40088
Y176
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Rhesus Macaque
Macaca mulatta
XP_001108258
337
38500
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P62137
330
37522
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Rat
Rattus norvegicus
P62138
330
37494
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506012
354
40218
Y175
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Chicken
Gallus gallus
NP_001006190
323
36981
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Frog
Xenopus laevis
Q7SZ10
323
36919
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Zebra Danio
Brachydanio rerio
XP_700468
242
27469
L89
L
L
E
L
E
A
P
L
K
I
C
G
D
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48461
327
37351
Y142
Y
D
E
C
K
R
R
Y
T
I
K
L
W
K
T
Honey Bee
Apis mellifera
XP_392943
329
37410
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Nematode Worm
Caenorhab. elegans
P48727
333
37773
Y143
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Sea Urchin
Strong. purpuratus
XP_791029
330
37658
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P22198
316
35745
F141
Y
D
E
C
K
R
R
F
S
V
K
L
W
K
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48482
312
35513
F150
Y
D
E
C
K
R
R
F
S
V
R
L
W
K
V
Baker's Yeast
Sacchar. cerevisiae
P32598
312
35889
Y143
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Conservation
Percent
Protein Identity:
100
90.9
94
N.A.
N.A.
91.8
92.1
N.A.
88.1
99
99
58.2
N.A.
88.6
91.4
89.4
88.4
Protein Similarity:
100
90.9
94.9
N.A.
N.A.
94.2
94.2
N.A.
89.5
99.6
100
61.2
N.A.
93.5
94.2
93.6
93.6
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
93.3
100
100
100
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
100
100
20
N.A.
93.3
100
100
100
Percent
Protein Identity:
N.A.
73
N.A.
74.9
81.7
82.3
Protein Similarity:
N.A.
83.9
N.A.
84.2
89.4
89.7
P-Site Identity:
N.A.
80
N.A.
66.6
100
100
P-Site Similarity:
N.A.
100
N.A.
93.3
100
100
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
95
0
0
0
0
0
0
6
0
0
0
0
% C
% Asp:
0
95
0
0
0
0
0
0
0
0
0
0
6
0
0
% D
% Glu:
0
0
100
0
6
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
0
0
0
0
0
0
0
0
0
89
0
0
0
6
0
% I
% Lys:
0
0
0
0
95
0
0
0
6
0
89
0
0
95
0
% K
% Leu:
6
6
0
6
0
0
0
6
0
0
0
95
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
95
95
0
0
0
6
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
89
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
95
0
0
% W
% Tyr:
95
0
0
0
0
0
0
83
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _